Dr. Kane is the Ling/Obrzut Assistant Professor at the Institute for Systems Biology, where her lab studies the biological determinants of frailty in both sexes. The Bruce McEwen Fellowship will support a new collaboration with the Bartolomucci lab at the University of Minnesota to learn practical skills in the assessment of social stress and social interactions in mice. This knowledge will be applied to ongoing longitudinal aging mouse studies in her lab, in order to explore the association between other functional measures of aging and social aging, and also to identify molecular factors associated with the social frailty index.